12. When the necessary requirements are fulfilled such as substitu-

tion and integration in the equation, estimate accurately the

kLa value with plotting the logarithmic values of (C^*  C1)/

(C^*  C2) versus time interval (t2  t1) (Fig. 2).

13. Take the slope of this straight line plot as kLa value.

Fig. 1 The plot of C values at different time intervals. C1, oxygen concentration measured at t1 time during

reoxygenation; C2, oxygen concentration at t2 time during reoxygenation

Fig. 2 Determination of kLa value based on the linearized plot of the logarithmic values of DO concentrations.

The slope of the obtained plot is directly proportional to the kLa value

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Aysegul Inam et al.